When you have Apotheosis + all its prerequisites (regardless of if you have patchouli + attribute fix installed), and you hover over the text box under world name in the world generation screen, your log will get spammed by:

@ Render
65539: Invalid key -1
########## GL ERROR ##########

Minecraft Version: 1.21.1
NeoForge Version: 21.1.184

Mod Versions:

• Placebo: 9.8.1
• Apothic Attributes: 2.8.1
• Apothic Spawners: 1.3.0
• Apothic Enchanting: 1.4.3
• Apotheosis: 21.1.2
• PrickleMC: 21.1.8
• Bookshelf: 21.1.65
• AttributeFix: 21.1.2
• Patchouli: 1.21-87-NeoForge

Your Neoforge version isn't the latest version anymore, 21.1.185 is the latest now. So possibly try to update Neoforge

Apoth does no rendering in the world load screen. I suspect you have another mod causing this problem.

Update: Log Begone solves this issue