When auto crafting items, even simple items, pressing the "next" button in the UI takes between 20-60 seconds to take you to the next screen. It seems like its getting worse the future i progress my game.
Using a crafting card in any of my busses completely bricks the game.

To Reproduce
I am unsure how to reproduce it, i have removed all crafting recipes besides one crafting table with same result. I have a medium base with some 50-100 machines connected to AE.

I also disabled channels in ae configs.

Expected behavior
I expect it to take a few seconds for small items and longer for more complex items.

Additional context
Profile started just before i issued a 100 item craft, and ended just after.

---- Minecraft Profiler Results ----
// Now with the same numbers

Time span: 28122 ms
Tick span: 206 ticks
// This is approximately 7.33 ticks per second. It should be 20 ticks per second

--- BEGIN PROFILE DUMP ---

[00] jobs - 79.41%/79.41%
[01] | unspecified - 100.00%/79.41%
[01] | rest - 0.00%/0.00%
[02] | | unspecified - 90.93%/0.00%
[02] | | chunkCheck - 9.07%/0.00%
[01] | move - 0.00%/0.00%
[01] | chunkCheck - 0.00%/0.00%
[00] levels - 19.23%/19.23%
[01] | Winner - 99.80%/19.19%
[02] | | tick - 94.48%/18.13%
[03] | | | entities - 43.86%/7.95%
[04] | | | | blockEntities - 91.66%/7.29%
[05] | | | | | ccmp:saved_multipart - 32.71%/2.38%
[05] | | | | | minecraft:tilemachinecontroller - 17.97%/1.31%
[05] | | | | | unspecified - 7.26%/0.53%
[05] | | | | | enderio:tile_conduit_bundle - 7.20%/0.53%
[06] | | | | | | tick - 55.68%/0.29%
[06] | | | | | | crazypants_enderio_conduits_conduit_liquid_LiquidConduit - 17.27%/0.09%
[07] | | | | | | | unspecified - 92.58%/0.08%
[07] | | | | | | | updateNetwork - 5.09%/0.00%
[07] | | | | | | | updateConnections - 2.33%/0.00%
[06] | | | | | | unspecified - 15.79%/0.08%
[06] | | | | | | crazypants_enderio_conduits_conduit_item_ItemConduit - 10.08%/0.05%
[07] | | | | | | | unspecified - 74.75%/0.04%
[07] | | | | | | | updateNetwork - 17.69%/0.01%
[07] | | | | | | | updateConnections - 7.56%/0.00%
[06] | | | | | | crazypants_enderio_conduits_conduit_power_PowerConduit - 1.19%/0.01%
[07] | | | | | | | unspecified - 80.11%/0.00%
[07] | | | | | | | updateNetwork - 15.06%/0.00%
[07] | | | | | | | updateConnections - 4.83%/0.00%
[05] | | | | | xu2:tileuse - 5.21%/0.38%
[05] | | | | | compacter:cobbler - 4.74%/0.35%
[05] | | | | | compacter:compacter - 3.34%/0.24%
[05] | | | | | randomthings:spectrecoil - 3.34%/0.24%
[05] | | | | | industrialforegoing:crop_recolector_tile - 2.86%/0.21%
[05] | | | | | quantumflux:qftile_imaginarytime - 2.28%/0.17%
[06] | | | | | | unspecified - 73.66%/0.12%
[06] | | | | | | lighting - 26.34%/0.04%
[07] | | | | | | | brightening - 44.91%/0.02%
[07] | | | | | | | darkening - 31.58%/0.01%
[07] | | | | | | | unspecified - 18.84%/0.01%
[07] | | | | | | | checking - 4.67%/0.00%
[05] | | | | | tp:emerald_cobblegen_block - 1.95%/0.14%
[05] | | | | | minecraft:block_crucible - 1.12%/0.08%
[05] | | | | | minecraft:ender tank - 1.04%/0.08%
[05] | | | | | minecraft:tilebonsaipot - 0.83%/0.06%
[05] | | | | | thermalexpansion:machine_pulverizer - 0.79%/0.06%
[05] | | | | | minecraft:block_barrel - 0.78%/0.06%
[06] | | | | | | lighting - 77.03%/0.04%
[07] | | | | | | | unspecified - 53.41%/0.02%
[07] | | | | | | | checking - 18.66%/0.01%
[07] | | | | | | | brightening - 17.24%/0.01%
[07] | | | | | | | darkening - 10.70%/0.00%
[06] | | | | | | unspecified - 22.97%/0.01%
[05] | | | | | yabba:item_barrel - 0.55%/0.04%
[05] | | | | | industrialforegoing:sludge_refiner_tile - 0.50%/0.04%
[05] | | | | | magneticraft:electric_cable - 0.49%/0.04%
[05] | | | | | enderio:tile_vacuum_chest - 0.43%/0.03%
[06] | | | | | | unspecified - 54.03%/0.02%
[06] | | | | | | tasks - 26.66%/0.01%
[06] | | | | | | redstoneCheck - 17.81%/0.01%
[06] | | | | | | sideIO - 1.50%/0.00%
[05] | | | | | embers:tile_entity_item_pump - 0.40%/0.03%
[05] | | | | | embers:tile_entity_boiler_bottom - 0.31%/0.02%
[05] | | | | | furnaceoverhaul:zenith_furnace - 0.31%/0.02%
[06] | | | | | | unspecified - 99.60%/0.02%
[06] | | | | | | checkLight - 0.40%/0.00%
[05] | | | | | industrialforegoing:enchantment_invoker_tile - 0.30%/0.02%
[05] | | | | | actuallyadditions:displaystand - 0.26%/0.02%
[05] | | | | | lootbags:tileentityopener - 0.21%/0.02%
[05] | | | | | embers:tile_entity_beam_cannon - 0.16%/0.01%
[05] | | | | | minecraft:extendedcraftingender_crafter - 0.14%/0.01%
[05] | | | | | ae2stuff:inscriber - 0.14%/0.01%
[05] | | | | | minecraft:landcraft_landia_portal_marker - 0.12%/0.01%
[05] | | | | | enderio:tile_sag_mill - 0.12%/0.01%
[06] | | | | | | sideIO - 45.99%/0.00%
[07] | | | | | | | pull - 55.68%/0.00%
[08] | | | | | | | | unspecified - 69.89%/0.00%
[08] | | | | | | | | from_appeng_tile_networking_TileCableBus - 30.11%/0.00%
[09] | | | | | | | | | unspecified - 73.42%/0.00%
[09] | | | | | | | | | to_sagmill_TileSagMillNormal - 26.58%/0.00%
[07] | | | | | | | unspecified - 33.88%/0.00%
[07] | | | | | | | push - 10.44%/0.00%
[06] | | | | | | unspecified - 36.50%/0.00%
[06] | | | | | | redstoneCheck - 8.94%/0.00%
[06] | | | | | | tasks - 8.57%/0.00%
[05] | | | | | mekanism:metallurgic_infuser - 0.11%/0.01%
[05] | | | | | embers:tile_entity_pump - 0.10%/0.01%
[05] | | | | | enderio:tile_alloy_smelter_enhanced - 0.09%/0.01%
[06] | | | | | | unspecified - 64.16%/0.00%
[06] | | | | | | tasks - 20.00%/0.00%
[06] | | | | | | redstoneCheck - 14.29%/0.00%
[06] | | | | | | sideIO - 1.54%/0.00%
[05] | | | | | embers:tile_entity_item_pipe - 0.09%/0.01%
[05] | | | | | actuallyadditions:empowerer - 0.09%/0.01%
[05] | | | | | embers:tile_entity_pipe - 0.09%/0.01%
[05] | | | | | minecraft:tileenergyinputhatch - 0.09%/0.01%
[05] | | | | | embers:tile_entity_receiver - 0.08%/0.01%
[05] | | | | | rftools:powercell - 0.08%/0.01%
[05] | | | | | magneticraft:hydraulic_press - 0.08%/0.01%
[05] | | | | | minecraft:ec_automation_interface - 0.07%/0.01%
[05] | | | | | thermalexpansion:machine_crucible - 0.07%/0.00%
[05] | | | | | astralsorcery:tilecollectorcrystal - 0.06%/0.00%
[05] | | | | | magneticraft:battery - 0.06%/0.00%
[05] | | | | | thermalexpansion:machine_insolator - 0.06%/0.00%
[05] | | | | | magneticraft:solar_panel - 0.06%/0.00%
[05] | | | | | embers:tile_entity_cinder_plinth - 0.06%/0.00%
[05] | | | | | tp:blaze_cobblegen_block - 0.06%/0.00%
[05] | | | | | magneticraft:oil_heater - 0.05%/0.00%
[05] | | | | | rftools:powercell_simple - 0.05%/0.00%
[05] | | | | | actuallyadditions:dropper - 0.05%/0.00%
[05] | | | | | magneticraft:refinery - 0.04%/0.00%
[05] | | | | | ae2stuff:grower - 0.04%/0.00%
[05] | | | | | embers:tile_entity_emitter - 0.04%/0.00%
[05] | | | | | minecraft:chest - 0.04%/0.00%
[05] | | | | | draconicevolution:celestial_manipulator - 0.03%/0.00%
[05] | | | | | xu2:tilemachinereceiver - 0.03%/0.00%
[05] | | | | | minecraft:skull - 0.03%/0.00%
[05] | | | | | actuallyadditions:fishingnet - 0.03%/0.00%
[05] | | | | | chickenchunks:chunkloader - 0.03%/0.00%
[05] | | | | | industrialforegoing:fluiddictionary_converter_tile - 0.03%/0.00%
[05] | | | | | actuallyadditions:reconstructor - 0.03%/0.00%
[05] | | | | | embers:tile_entity_alchemy_tablet - 0.02%/0.00%
[05] | | | | | openblocks:trophy - 0.02%/0.00%
[05] | | | | | thermalexpansion:machine_transposer - 0.02%/0.00%
[05] | | | | | embers:tile_entity_alchemy_pedestal - 0.02%/0.00%
[05] | | | | | lordcraft:tile_15 - 0.02%/0.00%
[05] | | | | | minecraft:neutron_collector - 0.02%/0.00%
[05] | | | | | thermalexpansion:machine_smelter - 0.02%/0.00%
[05] | | | | | thermalexpansion:machine_compactor - 0.02%/0.00%
[05] | | | | | embers:tile_entity_boiler_top - 0.02%/0.00%
[05] | | | | | thermalexpansion:machine_enchanter - 0.01%/0.00%
[05] | | | | | rftools:crafter3 - 0.01%/0.00%
[05] | | | | | thermalexpansion:machine_extruder - 0.01%/0.00%
[05] | | | | | lordcraft:tile_5 - 0.01%/0.00%
[04] | | | | regular - 4.12%/0.33%
[05] | | | | | tick - 93.93%/0.31%
[06] | | | | | | unspecified - 55.91%/0.17%
[06] | | | | | | travel - 11.51%/0.04%
[07] | | | | | | | rest - 50.84%/0.02%
[08] | | | | | | | | unspecified - 97.03%/0.02%
[08] | | | | | | | | chunkCheck - 2.97%/0.00%
[07] | | | | | | | move - 31.95%/0.01%
[07] | | | | | | | unspecified - 17.21%/0.01%
[06] | | | | | | ai - 9.43%/0.03%
[07] | | | | | | | newAi - 93.65%/0.03%
[08] | | | | | | | | controls - 41.54%/0.01%
[09] | | | | | | | | | move - 49.86%/0.01%
[09] | | | | | | | | | unspecified - 25.15%/0.00%
[09] | | | | | | | | | look - 17.16%/0.00%
[09] | | | | | | | | | jump - 7.84%/0.00%
[08] | | | | | | | | unspecified - 25.47%/0.01%
[08] | | | | | | | | targetSelector - 13.60%/0.00%
[09] | | | | | | | | | unspecified - 58.64%/0.00%
[09] | | | | | | | | | goalSetup - 41.36%/0.00%
[08] | | | | | | | | goalSelector - 6.74%/0.00%
[09] | | | | | | | | | unspecified - 60.58%/0.00%
[09] | | | | | | | | | goalSetup - 39.42%/0.00%
[08] | | | | | | | | checkDespawn - 5.56%/0.00%
[08] | | | | | | | | navigation - 3.10%/0.00%
[08] | | | | | | | | sensing - 2.29%/0.00%
[08] | | | | | | | | mob tick - 1.71%/0.00%
[07] | | | | | | | unspecified - 6.35%/0.00%
[06] | | | | | | move - 6.21%/0.02%
[06] | | | | | | rest - 5.75%/0.02%
[07] | | | | | | | unspecified - 94.78%/0.02%
[07] | | | | | | | chunkCheck - 5.22%/0.00%
[06] | | | | | | entityBaseTick - 5.73%/0.02%
[07] | | | | | | | unspecified - 91.69%/0.02%
[07] | | | | | | | portal - 8.31%/0.00%
[06] | | | | | | livingEntityBaseTick - 3.85%/0.01%
[06] | | | | | | mobBaseTick - 0.58%/0.00%
[06] | | | | | | chunkCheck - 0.28%/0.00%
[06] | | | | | | headTurn - 0.24%/0.00%
[06] | | | | | | looting - 0.21%/0.00%
[06] | | | | | | push - 0.15%/0.00%
[06] | | | | | | jump - 0.08%/0.00%
[06] | | | | | | rangeChecks - 0.07%/0.00%
[05] | | | | | unspecified - 5.57%/0.02%
[05] | | | | | remove - 0.50%/0.00%
[04] | | | | players - 3.96%/0.32%
[05] | | | | | tick - 99.16%/0.31%
[06] | | | | | | unspecified - 99.50%/0.31%
[06] | | | | | | chunkCheck - 0.50%/0.00%
[05] | | | | | unspecified - 0.74%/0.00%
[05] | | | | | remove - 0.10%/0.00%
[04] | | | | unspecified - 0.18%/0.01%
[04] | | | | remove - 0.06%/0.00%
[04] | | | | global - 0.01%/0.00%
[04] | | | | pendingBlockEntities - 0.01%/0.00%
[03] | | | mobSpawner - 36.72%/6.66%
[04] | | | | unspecified - 99.88%/6.65%
[04] | | | | lighting - 0.12%/0.01%
[05] | | | | | darkening - 68.28%/0.01%
[05] | | | | | brightening - 24.46%/0.00%
[05] | | | | | unspecified - 3.85%/0.00%
[05] | | | | | checking - 3.41%/0.00%
[03] | | | unspecified - 13.90%/2.52%
[03] | | | tickBlocks - 3.72%/0.68%
[04] | | | | pollingChunks - 97.34%/0.66%
[05] | | | | | unspecified - 46.84%/0.31%
[05] | | | | | tickBlocks - 24.89%/0.16%
[06] | | | | | | unspecified - 94.65%/0.15%
[06] | | | | | | randomTick - 5.35%/0.01%
[07] | | | | | | | unspecified - 97.69%/0.01%
[07] | | | | | | | lighting - 2.31%/0.00%
[08] | | | | | | | | unspecified - 61.07%/0.00%
[08] | | | | | | | | checking - 22.79%/0.00%
[08] | | | | | | | | darkening - 9.00%/0.00%
[08] | | | | | | | | brightening - 7.14%/0.00%
[05] | | | | | forcedChunkLoading - 9.56%/0.06%
[05] | | | | | regularChunkLoading - 5.75%/0.04%
[05] | | | | | tickChunk - 5.17%/0.03%
[05] | | | | | iceandsnow - 3.03%/0.02%
[06] | | | | | | unspecified - 97.77%/0.02%
[06] | | | | | | lighting - 2.23%/0.00%
[07] | | | | | | | unspecified - 55.23%/0.00%
[07] | | | | | | | checking - 30.53%/0.00%
[07] | | | | | | | darkening - 7.38%/0.00%
[07] | | | | | | | brightening - 6.85%/0.00%
[05] | | | | | getChunk - 1.96%/0.01%
[05] | | | | | thunder - 1.47%/0.01%
[05] | | | | | checkNextLight - 1.34%/0.01%
[04] | | | | unspecified - 2.14%/0.01%
[04] | | | | playerCheckLight - 0.53%/0.00%
[03] | | | chunkMap - 0.97%/0.18%
[03] | | | Zero CORE|Multiblock|Tick - 0.32%/0.06%
[04] | | | | Extreme Reactors|Reactor update - 78.82%/0.05%
[05] | | | | | RadiateRod - 42.28%/0.02%
[05] | | | | | unspecified - 19.81%/0.01%
[05] | | | | | Heat - 12.26%/0.01%
[05] | | | | | SendPower - 10.41%/0.00%
[05] | | | | | Waste&Fuel - 6.10%/0.00%
[05] | | | | | Tickables - 4.23%/0.00%
[05] | | | | | RefCoords - 1.89%/0.00%
[05] | | | | | Updates - 1.06%/0.00%
[05] | | | | | SendFluid - 0.88%/0.00%
[05] | | | | | sendTickUpdate - 0.55%/0.00%
[05] | | | | | updateFuelAssembliesQuota - 0.54%/0.00%
[04] | | | | unspecified - 21.18%/0.01%
[03] | | | chunkSource - 0.24%/0.04%
[03] | | | tickPending - 0.14%/0.03%
[04] | | | | unspecified - 69.83%/0.02%
[04] | | | | ticking - 18.91%/0.00%
[04] | | | | cleaning - 11.26%/0.00%
[03] | | | portalForcer - 0.05%/0.01%
[03] | | | village - 0.05%/0.01%
[03] | | | Zero CORE|Multiblock|DetachedParts - 0.02%/0.00%
[03] | | | Zero CORE|Multiblock|Merge - 0.01%/0.00%
[03] | | | Zero CORE|Multiblock|Split&Assembly - 0.00%/0.00%
[03] | | | Zero CORE|Multiblock|DeadControllers - 0.00%/0.00%
[02] | | tracker - 5.43%/1.04%
[02] | | unspecified - 0.08%/0.02%
[02] | | timeSync - 0.01%/0.00%
[01] | unspecified - 0.20%/0.04%
[00] connection - 1.13%/1.13%
[01] | unspecified - 92.05%/1.04%
[01] | travel - 4.73%/0.05%
[02] | | rest - 39.76%/0.02%
[03] | | | unspecified - 93.03%/0.02%
[03] | | | chunkCheck - 6.97%/0.00%
[02] | | unspecified - 31.01%/0.02%
[02] | | move - 29.23%/0.02%
[01] | livingEntityBaseTick - 1.63%/0.02%
[01] | entityBaseTick - 0.85%/0.01%
[02] | | unspecified - 90.93%/0.01%
[02] | | portal - 9.07%/0.00%
[01] | ai - 0.26%/0.00%
[02] | | unspecified - 63.25%/0.00%
[02] | | newAi - 36.75%/0.00%
[01] | push - 0.15%/0.00%
[01] | keepAlive - 0.11%/0.00%
[01] | headTurn - 0.09%/0.00%
[01] | chunkCheck - 0.07%/0.00%
[01] | jump - 0.02%/0.00%
[01] | rangeChecks - 0.02%/0.00%
[00] ServerTickEvent_END - 0.19%/0.19%
[01] | PowerConduitNetwork - 48.14%/0.09%
[02] | | sendEnergy - 79.43%/0.07%
[03] | | | unspecified - 72.40%/0.05%
[03] | | | com_cjm_overloaded_block_tile_infinity_TileInfiniteCapacitor - 15.48%/0.01%
[03] | | | appeng_tile_networking_TileEnergyAcceptor - 5.33%/0.00%
[03] | | | lumien_randomthings_tileentity_TileEntitySpectreEnergyInjector - 3.04%/0.00%
[03] | | | trackEnergy - 2.72%/0.00%
[03] | | | erogenousbeef_bigreactors_common_multiblock_tileentity_TileEntityReactorPowerTapRedstoneFlux - 1.02%/0.00%
[02] | | unspecified - 11.15%/0.01%
[02] | | updateNetworkStorage - 2.28%/0.00%
[02] | | capSupplyInit - 2.27%/0.00%
[02] | | checkReceptors - 1.62%/0.00%
[02] | | trackEnergy - 1.48%/0.00%
[02] | | conduitUpdate - 1.09%/0.00%
[02] | | capBankUpdate - 0.68%/0.00%
[01] | ItemConduitNetwork - 36.73%/0.07%
[02] | | NetworkedInventoryTick_net_minecraftforge_items_wrapper_InvWrapper - 89.18%/0.06%
[02] | | unspecified - 10.82%/0.01%
[01] | unspecified - 8.74%/0.02%
[01] | LiquidConduitNetwork - 6.40%/0.01%
[02] | | unspecified - 73.34%/0.01%
[02] | | flow - 26.66%/0.00%
[00] ServerTickEvent_START - 0.02%/0.02%
[01] | unspecified - 84.46%/0.02%
[01] | ItemConduitNetwork - 10.72%/0.00%
[01] | LiquidConduitNetwork - 3.71%/0.00%
[01] | PowerConduitNetwork - 1.10%/0.00%
[00] unspecified - 0.02%/0.02%
[00] commandFunctions - 0.00%/0.00%
[00] tallying - 0.00%/0.00%
[00] tickables - 0.00%/0.00%
[00] snooper - 0.00%/0.00%
[00] dim_unloading - 0.00%/0.00%
[00] players - 0.00%/0.00%
--- END PROFILE DUMP ---

Environment
Self hosted Project ozone 3 running version 3.2.55
We are two players sharing the same base.

• Minecraft Version: 1.12.2
• AE2 Version: appliedenergistics2-rv6-stable-7.jar
• Forge Version: 14.23.5.2847

The profiler dump is pretty much worthless. We need an actual sampling or profiling dump from something like jvisualvm or potentially the sampler mod for minecraft.

Otherwise it is just guessing. But on idea I actually have would be some external inventory.
There were a couple, which would have a major performance impact in AE2. But I sadly cannot remember which ones currently. But usually stuff which stores large amounts of different items.