I discovered that with the new perk tree, you are prevented from breaking blocks if both Gelu and Evorsio are taken. Sealing either with a sigil fixes the problem. I went from Vicio through the singularity node to reach Evorsio, in case that matters. Thanks!

Direwolf 20 1.12 mod pack through Twitch
Forge V. 14.23.5.2781
Astral Sorcery V. 1.12.2-1.10.10