It's as the title says. I entered a regular Minecraft world on 1.21.5, and decided to press the Escape key, which apparently crashed the game. I've isolated this issue to be caused by using Cardinal Components API and Sodium/Lithium together in any occasion.

Steps to reproduce the crash:

1. Install Fabric Loader for Minecraft 1.21.5, and place Sodium, Lithium and Cardinal Components API in your mods folder
2. Open the game. It should load up like normal
3. Create/open any world, and once it loads, try pressing Escape to manually save your game
4. Experience the crash for yourself

Crash Log link from the testing: https://mclo.gs/s1ikLD5
Latest Log file of the same test below, just in case:

latest.log