Disabling and Enabling "Show New Messages" in the "General" settings will break everything for Twitch Integration. Enabling the setting will not make messages show up again unless you disconnect from Twitch completely, delete all the channels and add them back.

Actually it seems worse then that, adjusting any setting in the General section seems to remove all of the Twitch Integration in the views:

It seems like they should always remain in views and just show as disabled if there's a problem with them... They still show in the text list: