Inv tweaks will not work and crashes minecraft. Forge, Rei Minimap, and optfine being used.

No one can help you if you don't include a crash log...

Here it is

---- Minecraft Crash Report ----
// I just don't know what went wrong :(

Time: 7/12/13 1:04 PM
Description: Exception in server tick loop

java.lang.NullPointerException
at net.minecraft.server.MinecraftServer.c(SourceFile:800)
at bkw.a(IntegratedServer.java:115)
at bkw.d(IntegratedServer.java:139)
at net.minecraft.server.MinecraftServer.run(SourceFile:314)
at hh.run(SourceFile:582)

A detailed walkthrough of the error, its code path and all known details is as follows:

-- System Details --
Details:
Minecraft Version: 1.6.2
Operating System: Mac OS X (x86_64) version 10.7.5
Java Version: 1.6.0_51, Apple Inc.
Java VM Version: Java HotSpot(TM) 64-Bit Server VM (mixed mode), Apple Inc.
Memory: 314528288 bytes (299 MB) / 362676224 bytes (345 MB) up to 362676224 bytes (345 MB)
JVM Flags: 2 total; -Xms350m -Xmx350m
AABB Pool Size: 0 (0 bytes; 0 MB) allocated, 0 (0 bytes; 0 MB) used
Suspicious classes: IWrUpdater, Config, WrUpdaterThreaded, ...[cpw.mods.fml.client.FMLClientHandler, CustomModLoadingErrorDisplayException, GuiWrongMinecraft, ...], [cpw.mods.fml.client.registry.ISimpleBlockRenderingHandler, RenderingRegistry], [cpw.mods.fml.common.LoaderException, FMLCommonHandler, TickType, ...], [cpw.mods.fml.common.modloader.BaseModProxy], [cpw.mods.fml.common.network.FMLPacket, EntitySpawnPacket, EntitySpawnAdjustmentPacket, ...], [cpw.mods.fml.common.registry.EntityRegistration], [cpw.mods.fml.common.toposort.ModSortingException], [cpw.mods.fml.relauncher.Side], [net.minecraftforge.client.ForgeHooksClient, ItemRenderType, IItemRenderer, ...], [net.minecraftforge.client.event.DrawBlockHighlightEvent, RenderWorldLastEvent, TextureStitchEvent, ...], [net.minecraftforge.common.MinecraftForge, ForgeInternalHandler, ForgeHooks, ...], [net.minecraftforge.event.EventBus, IEventListener, ListenerList, ...], [net.minecraftforge.event.entity.EntityEvent], [net.minecraftforge.event.entity.item.ItemEvent, ItemTossEvent], [net.minecraftforge.event.entity.living.LivingEvent, LivingSetAttackTargetEvent, LivingUpdateEvent, ...], [net.minecraftforge.event.world.WorldEvent, Load, Unload, ...], [net.minecraftforge.fluids.FluidRegistry, FluidRegisterEvent, Fluid, ...], [reifnsk.minimap.ReiMinimap, GuiScreenInterface, GuiOptionScreen, ...]
IntCache: cache: 0, tcache: 0, allocated: 0, tallocated: 0
Profiler Position: N/A (disabled)
Player Count: 0 / 8; []
Type: Integrated Server (map_client.txt)
Is Modded: Very likely; Jar signature invalidated

Forge is not installed correctly, as shown by your log showing bkw. instead of net.minecraft.server.integrated.IntegratedServer

Use the forge installer and import that profile into whatever launcher you're using.