Placing a Factorization Barrel inside a Cardboard Box cause the tile entity data to be lost. When re-placed, an "empty" hitbox appears. When attempting to interact with the entity, an on-screen message is displayed indicating that the tile entity data has been lost, and that it can only be recovered by cheating.

The 'hitbox' barrel can be broken, and replaced to get functionality back, but the contents are lost.

Closing, as this does not appear to be an issue with JABBA barrels.