I haven't tested if the actual flow of gas stops, but when I use the configurator on a gas pipe telling it to disable the connection to another pipe, it don't visually show what's going on.
Most other transport pipes in other plugins have a way of showing whether it's disabled/input/output, etc. but not gas pipes.
It's a pain to use microblocks to separate the pipes, because that's the only thing that helps me to visualize what's going on.

Connection states only work on connected acceptors or outputters, not other transmitters (in your case, Pressurized Tubes) - this is the same for cables, pipes and transporters too.

Then in my opinion it's a bug that right clicking with the configurator between pressurized tubes toggles the state. That is, a message about the connection state is logged in the chat.

For a long time I thought it was a bug that the connection state said "NONE", and still, gas was flowing between the pipes.