Putting Depleted Uranium Nuclear Fuel in a Fuel Reprocessor will crash the game.
According to some of our E2E users, it also does world corruption (can't confirm or deny).

Also tested in a closed test environment.
https://pastebin.com/ffyhZzkp

Ah, found the issue, will be fixed for the next release (hopefully/probably tomorrow morning). If this does crash worlds on load, the fix should undo that :)

Thank you for the quick reply. This really messed with my E2E progression, and we had to rollback our server removing a lot of progress made by one of the players, as well as my own.

2.10p has been uploaded and should be available on CurseForge shortly :)