Stack-Trace
java.lang.NoSuchMethodError: net.fabricmc.loader.FabricLoader.getGameProvider()Lnet/fabricmc/loader/game/GameProvider;
at me.modmuss50.optifabric.mod.OptifineSetup.getLaunchMinecraftJar(OptifineSetup.java:275)
at me.modmuss50.optifabric.mod.OptifineSetup.getMinecraftJar(OptifineSetup.java:253)
at me.modmuss50.optifabric.mod.OptifineSetup.getRuntime(OptifineSetup.java:81)
at me.modmuss50.optifabric.mod.OptifabricSetup.run(OptifabricSetup.java:41)
at com.chocohead.mm.Plugin$$Lambda$46/934740803.accept(Unknown Source)
at java.util.ArrayList.forEach(ArrayList.java:1249)
at com.chocohead.mm.Plugin.getMixins(Plugin.java:340)
at org.spongepowered.asm.mixin.transformer.PluginHandle.getMixins(PluginHandle.java:128)
at org.spongepowered.asm.mixin.transformer.MixinConfig.postInitialise(MixinConfig.java:796)
at org.spongepowered.asm.mixin.transformer.MixinProcessor.prepareConfigs(MixinProcessor.java:568)
at org.spongepowered.asm.mixin.transformer.MixinProcessor.select(MixinProcessor.java:462)
at org.spongepowered.asm.mixin.transformer.MixinProcessor.checkSelect(MixinProcessor.java:438)
at org.spongepowered.asm.mixin.transformer.MixinProcessor.applyMixins(MixinProcessor.java:290)
at org.spongepowered.asm.mixin.transformer.MixinTransformer.transformClass(MixinTransformer.java:234)
at org.spongepowered.asm.mixin.transformer.MixinTransformer.transformClassBytes(MixinTransformer.java:202)
at net.fabricmc.loader.impl.launch.knot.KnotClassDelegate.getPostMixinClassByteArray(KnotClassDelegate.java:247)
at net.fabricmc.loader.impl.launch.knot.KnotClassDelegate.tryLoadClass(KnotClassDelegate.java:150)
at net.fabricmc.loader.impl.launch.knot.KnotClassLoader.loadClass(KnotClassLoader.java:155)
at java.lang.ClassLoader.loadClass(ClassLoader.java:357)
at java.lang.Class.forName0(Native Method)
at java.lang.Class.forName(Class.java:348)
at net.fabricmc.loader.impl.util.DefaultLanguageAdapter.create(DefaultLanguageAdapter.java:50)
at net.fabricmc.loader.impl.entrypoint.EntrypointStorage$NewEntry.getOrCreate(EntrypointStorage.java:117)
at net.fabricmc.loader.impl.entrypoint.EntrypointContainerImpl.getEntrypoint(EntrypointContainerImpl.java:53)
at net.fabricmc.loader.impl.entrypoint.EntrypointUtils.invoke0(EntrypointUtils.java:47)
at net.fabricmc.loader.impl.entrypoint.EntrypointUtils.invoke(EntrypointUtils.java:35)
at net.fabricmc.loader.impl.launch.knot.Knot.init(Knot.java:157)
at net.fabricmc.loader.impl.launch.knot.Knot.launch(Knot.java:71)
at net.fabricmc.loader.impl.launch.knot.KnotClient.main(KnotClient.java:23)

I do have other mods in the mods folder such as
-appleskin
-hydrogen
-mouse tweaks
-phosphor
-xaero's world map
-replaymod

Also is it possible to have optifine and lithium together?

same

what version of OptiFine are you trying to run, and what version MC are you loading??

the version of optifine is "OptiFine_1.16.5_HD_U_G8" and the version of mc im loading is 1.16.5

Same