Quark version: Quark-r1.6-179.jar
https://imgur.com/q7X4Fim

The "vazkii.quark.world.effects.PotionColorizer.onCalculateColor() - 11948 ms" suggests the colorizing event is probably eating as much as 5-10% of the server's processing power, and that's without anyone actually having those status effects. I cannot find a config option to disable them, sadly. I am not positive if 1.12 is still supported, and I'm sorry if it's not, but this is a pretty big deal for my modpack and its users, so I would greatly appreciate if you would look into it.

I can't help you on 1.12, I'm sorry.