Breaking an infuser with something inside of it does not drop the item nor keep the item in inventory, it's lost
Breaking a builder the inserted card is lost.

This may be related to a change mentioned by another mod dev:

mojang changed how tiles save data

in 1.17 and lower, you would override the save function, in 1.18 save still exists, but you need to override saveAdditional

its CompoundTag save(CompoundTag tag) vs void saveAdditional(CompoundTag tag)

BiggerSeries/BiggerReactors@07e7277

Fixed now