in my creative testing world,
i chained a few generator with 9 empty block separation (4 tick distance)
each hooked to a sequencer, which are hooked to the same 100ticks (5s) timer.
(with the first sequencer pointing to a pearl injector)
and tuned the sequencer for max RF/t in each generator.

but looking at the sequencer afterwards, the delay between each generator is inconsistent
varying from 3-5 ticks

what about having a block called Endergenic Stabilizer, which registers some generator and pearl injector, then tick them together?
then we can have the original generator as a not-so-stable generator, in which player have to sacrifice max efficiency to compensate the instability.

p.s. ender monitor also fail to output any signal when generator is receiving&launching in the same tick.

the above trial have a delay of (4,3,5,4,4)
then upon reload the world, it failed outputting max RF/t, i have to re-tune the sequencer
this time it has a delay of (3,6,4,4,4)...
according to the wiki,
i think the generator is suppose to have stable exact timing according to the distance?

The problem is most likely that there is no guarantee in which order tile entities are ticked and since this is so timing sensitive the 'in-tick' order can matter a lot. Not sure exactly how I'm going to solve this though. I'm thinking I probably need to handle the entire 'multiblock' ticking at once