I'm using minecraft 1.20.1 with SophisticatedStorage 0.10.20.778 and Mouse Tweaks 2.25.
SophisticatedStorage's golden chest has a scrollbar, mouse scrolling event will scroll the scrollbar rather than trigger other things like MouseTweak's wheel tweak(which move items between inventories).
Is there any settings to prevent scrolling of SophisticatedStorage, or not using scrollbar at all, like UI of IronChest?

Not using scrollbar at all is easy - it will only show when the gui can't fit on a screen so if you change the gui scale to smaller one that could help.
I will have to think about what to do with the other usecase of compatibility with mouse tweaks because I want players to be able to scroll in their backpack easily to see the additional slots without the need to always grab a scrollbar

Changing gui scale is not always a solution, sometimes smaller scale will be too small to read. I remembered IronChest use a wider ui(>12 cols) when gui can't fit, maybe that's a solution. I think adding some setting to let user config the scrolling behaviour may also help.