This is didn't appear without unimixins

crash :

crash-2023-10-07_13.06.15-client.txt

LoadingProfiler replaces every transformer in the transformer chain with wrapper objects of a single type. This is exactly as disastrous for compatibility as it sounds. There is nothing we can realistically do here, the mod is incompatible with Mixin as a whole. For example it will also crash with Et Futurum Requiem (which shades base Mixin 0.7.11).

I recommend DTools and LaunchTweaks as alternatives that do pretty much the same thing as LoadingProfiler without violently breaking everything.