An update on this; VulkanMod v0.4.8 for MC v1.21.1 works nicely alongside Xaero's Minimap v24.4.0 for the most part.

The only issue I've found so far is that the signature colors for each waypoint do not work.

With VulkanMod:

Without VulkanMod:

Not a dealbreaker or anything in my opinion, but there's that. Do you think it warrants an Issue ticket of its own, @xCollateral?

EDIT: I'm going to add the list of mods I tested VulkanMod with over here, just in case it's relevant or useful at all.

• All Arrows Infinity Fix
• Anvil Never Too Expensive
• Chunk Loaders
• Clumps
• Fabric API
• Fabric Language Kotlin
• JustEnoughItems
• Lightweight Inventory Sorting
• ModernFix
• SuperMartijn642's Config Lib
• SuperMartijn642's Core Lib
• Xaero's Minimap
• YetAnotherConfigLib
• Zoomify