Patch 11.0.0 added new macro restrictions which limit the usage of macro addons like M6.
There are workaround to get keybinds working again with M6 macros placed on Bartender bars, but clicking the macro buttons does not work any more.

M6 found a way to also allow clicking again with the default action bars. Bars from addons need to add support for that. Could you please add that support to Bartender?
More information here: https://www.patreon.com/posts/110408593 (at the end)