Low priority.

1. Create a blank/reset profile (may not be necessary but that's my scenario)
2. Go into config mode
3. Set Menu Bar 1 to Columns: 1 (I have it set vertically)
4. Note that the top 2 and bottom 2 buttons are active while the middle ones act as you'd expect in that mode; this doesn't happen when the bar is horizontal

I'm not sure what issue you are describing. What do you mean the top 2 and bottom 2 are "active"?

Never mind, I was able to duplicate it before but failed 3 times in a row when I was going to take a screenshot to demonstrate just now.