I usually play tank paladin in WotLK Classic, but sometimes play DPS - the meta for retri paladin is to spam taunt (Hand of Reckoning) on cooldown with the Glyph of Reckoning enabled, which has the effect "Your Hand of Reckoning spell no longer taunts the target and can deal damage to untauntable targets". Since normally I use this spell as an actual taunt I have the warnings for it turned on in RSA, which can get pretty annoying for my group mates when I'm DPSing an untauntable boss and helpfully announcing that it's immune every 8 seconds.

It would be nice to have an option in the settings for HoR to disable reporting resists/immunity when Glyph of Reckoning is active on your talent screen. (or even just change the default, I can't imagine a situation you'd want to announce target immunity when this glyph is active)

I know I can toggle the warning off when I'm playing ret, but this is tedious to do, and it's likely I'll forget to turn it back on. I am likely in the meantime to disable warnings entirely for HoR and find an independent weak aura to run my taunt warning that can be unloaded when Glyph of Reckoning is enabled. However I still think it would be a nice feature for RSA to handle this itself.

I'll have a look at how best to implement this sort of option, but is using two profiles not an option? In the profile tab of RSA's settings menu you can set independent profiles on a per-spec basis.

The intended use for that is so that you can have different setups depending on the role you're playing. Using defensives is generally less useful to warn about when you're playing DPS vs Tank for example.