Currently, the Reagent System is very finicky and is not very fun. It adds costs to the rituals, but in a roundabout way. There needs to be an initial improvement to the system where it is a lot more fluid to link different sources together to the various drains, and then a better way to meter out costs.

Also, more machines that run purely on Reagents sounds like a good idea.

[Idea/Suggestion for the problem] What if you made a sort of system where you could make flasks that refill when you kill a monster that has more than say 5 hearts (to prevent slime potion farming) you could make it so that every 25 or so uses you would have to "Recharge it" with quite a few reagents (to get the player to keep making more reagents) to balance it and make it so you would not have to use fillers so often.

And maybe you could also add a machine (or a Ritual) called something like "Alchemical Refiner" that makes reagents when you give it Life essence and Sacrifice a specific mob for a specific reagent (e.g. silverfish for terrae Blazes for Incendium etc.) that way players are encouraged to use the dagger of sacrifice and go searching for mobs

i hope these ideas inspire you to make something awesome p.s. i love blood magic

Reagent System replaced by Demonic Will System in recent versions.