Load up into a new world hoarded by zombies. The apocalypse is upon this world and you need the resources to survive.
As always, you need to scavenge resources from the world around you, but now you may find structures in which you can find guns, armor, and survival supplies in.
Guns are the most important thing, load yourself up with strong artillery by making guns and finding them around the world.
In addition, there are always Tinker's Construct tools and weapons to further build your loadout.
It's noticed that you don't lose your stuff when you die and the Creepers can't blow up blocks.
This way, you could build a fortified base with less of a threat, and even a fancy house on a hill if you please. There are chisels to further build your base and special MalisisDoors to make your base protected from the undead threat.
Resources are another important thing, whereas ores are quite important; go to the nether and find some new nether ores to help you in this terror land.
There are always some food options for survival, either eat the rations you may be able to scrounge up or go fancy and dive into Pam's HarvestCraft in tandem with Cooking for Blockheads to build your shelter a nice kitchen with various food options. Farming for Blockheads also allows you to purchase the entire range of seeds to choose from.
Then there's some tech you can dive into to power your base and keep yourself safe. There's Immersive Engineering, Ender IO, Refined Storage, and Extreme Reactors to build a reactor to power it all.
