If i decide to not use one of the frames they seem to position somewhat hardcoded. If e.g. Soul Shard is disabled they will always be in the bottom left corner. I haven't found a way to get them back to the player frame except disabling the addon.

Well, could it be possible to add a simple enabled/disabled checkbox, so one can decide whether or not EME should reposition the corresponding frame?

The checkbox doesn't mean it'll disable it, that is to hide it during edit mode. It should still position off where you placed it before unchecking the box.

If I do, you will have to /reload for it to start working. That ok?

Yeah that is totally fine. I don't want to enable/disable it on a regular basis.