I think it's more convenient to list which debuffs to hide than it is to choose which debuffs to show, especially during new content. Please can you add support, or would you accept a pull request?

Any update on this? When doing mythic dungeons it would be nice to keep the default blizzard debuffs that show up but specify a few to hide instead of having to add every mythic dungeon effect that I want to show up on party frame.

This would be an extremely nice feature to see. Specifically challengers burden and sated debuffs, which are unimportant.

I would accept pull requests, yes. I tend to show my debuffs based on group, i.e. Poison, Curse, etc, rather than individual spells.