Recently I have had my macros wiped when reloading addons. I've gone thru disabling and enabling macros until I was able to reproduce the issue. It seems that when GRM is enabled as an addon, and a reload is triggered, a GRM macro gets created and wipes out all existing macros. This is extremely inconvenient, especially if you do not have a backup of the macros.

The macro in question:

/run GRM.Report("Reserved for GRM Macro Tool Usage. Please do not delete.")